Reffo began her acting career in 1980 starring in supporting role in the telenovela Conflictos de un Medico, under the direction of Ernesto Alonso, and continued her career acting in Al Rojo vivo.
In 1983, Valentin Pimstein gave her the opportunity to star as the protagonist of La fiera as Natalia Ramirez together with Gulliermo Capetillo.
1985 she started in Carlos Tellez's telenovela, Juana Iris alongside Valentin Trujjilo and her sister, Gabriela Ruffo.
She worked in Ernesto Alonso's Victoria
Ernesto Alonso's offered her led role in the telenovela Simplemente Maria.
1990s
In 995 she was protagonist in Pobre Nina Rica a telenovela by Enrique Segoviano as Consuelo Villagran.
1998, She starred in telenovella, Vivo Por Elena, Elena Carvajal.
In 2000, she starred in Salvador Mejia's, Abrazame muy fuerte alongside Aracely Arambula.
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